Publications from this laboratory.



* = equal contribution authors; ° = co-corresponding authors 


(61) F.A.S. Engelhardt, F. Praetorius, C.H. Wachauf, G. Brüggenthies, F. Kohler, B. Kick, K.L. Kadletz, P. N. Pham, K. L. Behler, T. Gerling, and H. Dietz, ‘Custom-Size, Functional, and Durable DNA Origami with Design-Specific Scaffolds’,

ACS Nano (2019), doi 10.1021/acsnano.9b01025

[publisher website]

(60) K. Häussermann, G. Young, P. Kukura, and H. Dietz, ‘Dissecting FOXP2 oligomerization and DNA binding’,

Angewandte Chemie Intl. Edition (2019), doi 10.1002/anie.201901734

[publisher website]

(59) M. Lakemeyer, E. Bertosin, F. Möller, D. Balogh, R. Strasser, H. Dietz, and S.A. Sieber, ‘Tailored Peptide Phenyl Esters Block ClpXP Proteolysis by an Unusual Breakdown into a Heptamer–Hexamer Assembly’,

Angewandte Chemie Intl. Edition (2019), doi 10.1002/anie.201901056

[publisher website]

(58) T. Gerling and H. Dietz, ‘Reversible covalent stabilization of stacking contacts in DNA assemblies’,

Angewandte Chemie Intl. Edition (2019), doi 10.110/anie.201812463

[publisher website]


(57) T. Gerling, M. Kube, B. Kick, and H. Dietz, 'Sequence-programmable covalent bonding of designed DNA assemblies',

Science Advances (2018), vol 4, doi 10.1126/sciadv.aau1157

[publisher website]

(56) M. Schickinger, M. Zacharias, and H. Dietz, 'Tethered multi-fluorophore motion reveals equilibrium transition kinetics of single DNA double-helices',

Proc Natl Acad Sci USA (2018), E7512-E7521, doi 10.1073/pnas.1800585115

[publisher website]

(55) L. Bruetzel, P. Walker, T. Gerling, H. Dietz, and J. Lipfert, 'Time-Resolved Small-Angle X-Ray Scattering Reveals Millisecond Transitions of a DNA Origami Switch',

Nano Letters (2018), vol 18, p2672-2676, doi 10.1021/acs.nanolett.8b00592

[publisher website]

(54) B. Bräuning*, E. Bertosin*, F. Praetorius, C. Ihling, A. Schatt, A. Adler, K. Richter, A. Sinz, H. Dietz, and M. Groll, 'Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB',

Nature Communications (2018), vol 9, article #1806, doi 10.1038/s41467-018-04139-2

[publisher website]

(53) P. Ketterer*, A.N. Ananth*, D.S. Laman, A. Mishra, E. Bertosin, M. Ganji, J. van der Torre, P. Onck, H. Dietz°, and C. Dekker°, 'DNA origami scaffold for studying intrinsically disordered proteins of the nuclear pore complex',

Nature Communications (2018), vol 9, article #902, doi 10.1038/s41467-018-03313-w

[publisher website]

(52) H. Franquelim, A. Khmelinskaia, J.P. Sobczak, H. Dietz, and P. Schwille, 'Membrane sculpting by curved DNA origami scaffolds',

Nature Communications (2018), vol 9, article #811, doi 10.1038/s41467-018-03198-9

[publisher website]


(51) K. Wagenbauer, C. Sigl, and H. Dietz, 'Gigadalton-scale shape-programmable DNA assemblies',

Nature (2017), vol 552, p78-83, doi: 10.1038/nature24651

[publisher website] 

(50) F. Praetorius, B. Kick, K.L. Behler, M.N. Honemann, D. Weuster-Botz, and H. Dietz, 'Biotechnological mass-production of DNA origami',

Nature (2017), vol 552, p84-87, doi: 10.1038/nature24650

[publisher website]

(49) M. Endo, E.M. Willner, Y. Kamada, Y. Suzuki, T. Emura, K. Hidaka, H. Dietz, H. Sugiyama, 'Single-molecule observation of the photoregulated conformational dynamics of DNA origami nanoscissors',

Angewandte Chemie Intl. Edition (2017), vol 56, p15324-15328

[publisher website]

(48) K. Wagenbauer, F. Engelhardt, E. Stahl, V. Hechtl, P. Stoemmer, F. Seebacher, L. Meregalli, P. Ketterer, T. Gerling, and H. Dietz, 'How we make DNA origami', 

ChemBioChem (2017), doi 10.1002/cbic.201700377

[publisher website]

(47) M. Siavashpouri, C. Wachauf, M. Zakhary, F. Praetorius, H. Dietz°, and Z. Dogic°, 'Molecular engineering of chiral colloidal liquid crystals using DNA origami', 

Nature Materials, (2017), doi 10.1138/nmat4909

[publisher website]

(46) F. Praetorius and H. Dietz, 'Self-assembly of genetically encoded DNA-protein hybrid nanoscale shapes', 

Science, (2017), vol 355, doi 10.1126/science.aam5488

[publisher website]


(45) J. Funke, P. Ketterer, C. Lieleg, P. Korber, and H. Dietz,

'Exploring nucleosome unwrapping using DNA origami', 

Nano Letters, (2016), doi 10.1021/acs.nanolett.6b04169

[publisher website] 

(44) J. Funke*, P. Ketterer*, C. Lieleg*, S. Schunter, P. Korber°, and H. Dietz°, 'Uncovering the forces between nucleosomes using DNA origami', 

Science Advances, (2016), doi 10.1126/sciadv.1600974

[publisher website]

(43) T. Martin, T. Bharat, A. Joerger, X. Bai, F. Praetorius, A. Fersht, H. Dietz°, and S. Scheres°, 'The design of a molecular support for cryo-EM structure determination', 

Proc Natl Acad Sci USA, (2016), doi 10.1073/pnas.1612720113

[publisher website]

(42) B. Kick, S. Hensler, F. Praetorius, H. Dietz, and D. Weuster-Botz, 'Specific growth rate and multiplicity of infection affect high-cell-density fermentation with bacteriophage M13 for ssDNA production', 

Biotechnology and Bioengineering, (2016), doi 10.1002/bit.26200

[publisher website]

(41) F. Kilchherr, C. Wachauf, B. Pelz, M. Rief, M. Zacharias, and H. Dietz, 'Single-molecule dissection of stacking forces in DNA'

Science, (2016), doi 10.1126/science.aaf5508

[publisher website]

(40) S. Krishnan, D. Ziegler, V. Arnaut, T. Martin, K. Kapsner, K. Henneberg, A. Bausch, H. Dietz, and F. Simmel, 'Molecular transport through large-diameter DNA nanopores', 

Nature Communications, (2016), doi 10.1038/ncomms12787,

[publisher website]

(39) E. Stahl, F. Praetorius, C. de Oliveira-Mann, K. Hopfner, and H. Dietz, 'Impact of heterogeneity and lattice bond strength of DNA triangle crystallization',  

ACS Nano, (2016), doi 10.1021/acsnano.6b04787

[publisher website]

(38) L. Rodrigues, K. Kyriakos, F. Schneider, H. Dietz, G. Winter, C. Papadakis, and M. Hubert, 'Characterization of lipid-based hexosomes as versatile vaccine carriers', 

Mol. Pharmaceutics, (2016), doi 10.1021/acs.molpharmaceut.6b00716 

[publisher website] 

(37) L. Bruetzel, T. Gerling, S. Sedlak, P. Walker, W. Zheng, H. Dietz, and J. Lipfert, 'Conformational changes and flexibility of DNA devices observed by small-angle X‐ray scattering', 

Nano Letters, vol 16 (2016), p4871-4879, 

[publisher website]

(36) H. Dietz, 'Toward Applications for DNA Nanotechnology - More Bricks to Build with', 

ChemBioChem, vol 17 (2016), p1046-1047 

[publisher website] - editorial 

(35) P. Ketterer, E. Willner, and H. Dietz,

'Nanoscale rotary apparatus formed from tight-fitting 3D DNA components', 

Science Advances, vol 2 (2016), e1501209 

[publisher website]


(34) J. Funke and H. Dietz, 'Placing molecules with Bohr radius resolution using DNA origami', 

Nature Nanotechnology, (2015), doi 10.1038/nnano.2015.240 

[publisher website]

(33) H. Dietz, 'Nanoscale cable tacking'

Nature Nanotechnology, vol 10 (2015), p829-830, 

[publisher website] - comment on work by Gothelf and colleagues 

(32) J. Sobczak and H. Dietz

'DNA-nanoparticle crystals: Exploiting shape complementarity', 

Nature Materials, vol 14 (2015), p752-754,

[publisher website] - comment on work by Mirkin and Gang 

(31) B. Kick, F. Praetorius, H. Dietz, and D. Weuster-Botz

'Efficient production of single-stranded DNA as scaffolds for DNA origami', 

Nano Letters, vol 15 (2015), p4672-4676

[publisher website]

(30) T. Gerling, K. Wagenbauer, A. Neuner, and H. Dietz

'Dynamic DNA devices and assemblies formed by shape-complementary, non-basepairing 3D components'

Science, vol 347 (2015), p1446-1452

[publisher website]

(29) C. Lieleg, P. Ketterer, J. Nuebler, J. Ludwigsen, U. Gerland, H. Dietz, F. Mueller-Planitz, and P. Korber

'Nucleosome spacing generated by ISWI and CHD1 remodelers is constant regardless of nucleosome density'

Molecular and Cellular Biology, vol 35 (2015), 1588-1605

[publisher website] 


(28) C. Plesa, N. van Loo, P. Ketterer, H. Dietz, and C. Dekker

'Velocity of DNA during translocation through a solid state nanopore'

Nano Letters, (2014), doi 10.1021/nl504375c 

[publisher website]

(27) E. Stahl, T. Martin, F. Praetorius, and H. Dietz, 'Facile and scalable preparation of pure and dense DNA origami solutions', 

Angewandte Chemie Intl. Edn., vol 53 (2014), p12735

[publisher website]

(26) H. Cui, B. Seubert, E. Stahl, H. Dietz, U. Reuning, L. Moreno-Leon, M. Ilie, P. Hofman, H. Nagase, B. Mari, and A. Krüger, 'Tissue inhibitor of metalloproteinases-1 induces a pro-tumourigenic increase of miR-210 in lung adenocarcinoma cells and their exosomes', 

Oncogene, vol 34 (2014), p3640-3650 

[publisher website] 

(25) B. Shen, V. Linko, H. Dietz, and J. Toppari

'Dielectrophoretic trapping of multilayer DNA origami nanostructures and DNA origami -induced local destruction of silicon dioxide'

Electrophoresis, (2014), doi: 10.1002/elps.201400323 

[publisher website]

(24) K. Wagenbauer*, C. Wachauf*, and H. Dietz

'Quantifying Quality in DNA Self-Assembly'

Nature Communications, 5:3691 (2014), doi: 10.1038/ncomms4691 

[publisher website]

(23) C. Plesa, A. Adithya, V. Linko, C. Gulcher, A. Katan, H. Dietz, and C. Dekker, 'Ionic Permeability and Mechanical Properties of DNA Origami Nanoplates on Solid-State Nanopores'

ACS Nano, vol 8 (2014), p35

[publisher website]


(22) E. Pfitzner*, C. Wachauf*, F. Kilchherr*, B. Pelz, W. Shih, M. Rief, and H. Dietz, 'Rigid DNA beams for high-resolution single-molecule mechanics', 

Angewandte Chemie Intl. Edn., vol 52 (2013), p7766

[publisher website]

(21) V. Linko and H. Dietz, 'The enabled state of DNA nanotechnology', 

Curr Opin Biotechnol, (2013), doi: 10.1016/j.copbio.2013.02.001 

[publisher website]


(20) J. Sobczak, T. Martin, T. Gerling, and H. Dietz, 'Rapid folding of DNA into nanoscale shapes at constant temperature', 

Science, vol 338 (2012), p1458 

[publisher website]

(19) X. Bai, T. Martin, S. Scheres°, and H. Dietz°

'Cryo-EM structure of a 3D DNA-origami object'

P Natl Acad Sci USA, vol 109 (2012), 20012 

[publisher website]

(18) M. Langecker*, V. Arnaut*, T. Martin*, J. List, S. Renner, M. Mayer, H. Dietz°, and F. Simmel° 'Synthetic lipid membrane channels formed by designed DNA nanostructures'

Science, vol 338 (2012), p932 

[publisher website]

(17) T. Martin and H. Dietz

'Magnesium-free self-assembly of multi-layer DNA objects'

Nature Communications, vol 3 (2012), #1103 

[publisher website]

(16) R. Wei*, T. Martin*, U. Rant°, and H. Dietz°

'DNA origami gatekeepers for solid-state nanopores'

Angewandte Chemie Intl. Edn., vol 51 (2012), p4864

[publisher website] 

(15) D. Kim, F. Kilchherr, H. Dietz°, and M. Bathe°, 'Quantitative prediction of 3D solution shape and flexibility of nucleic acid nanostructures', 

Nucleic Acids Research, vol 40 (2012), p2862

[publisher website]


(14) M. Vukajlovic, H. Dietz, M. Schliwa, and Z. Ökten

'How kinesin-2 forms a stalk'

Molecular Biology of the Cell, vol 22 (2011), p4279 

[publisher website]

(13) C. Castro, F. Kilchherr, D. Kim, E. Shiao, T. Wauer, P. Wortmann, M. Bathe, and H. Dietz, 'A primer to scaffolded DNA origami', 

Nature Methods, vol 8 (2011), p221 

[publisher website]


F. Praetorius and H. Dietz.

'Scalable biotechnological production of DNA single strand molecules of defined sequence and length'



M. Langecker, V. Arnaut, T. Martin, F.C. Simmel, and H. Dietz.

'Nucleic acid based nanopores or transmembrane channels and their uses'

EP 2695949 A1 (granted)


M. Bathe, D.N. Kim, H. Dietz.

'Method and Apparatus for Controlling Properties of Nucleic Acid Nanostructures'

US Patent No. 12/976,737 (granted) 


H. Dietz and T. Liedl

'Modifying structures, preferably biocompatible three-dimensional microstructures in a matrix comprises providing matrix made of liquid matrix material, adding a liquid crosslinking agent using injection pipette and moving the pipette'

DE102008020665-A1 (pending decision)